Myles Garrett is only a tryout away from becoming a two-sport athlete … ’cause Ice Cube tells TMZ Sports he’d love to give the NFL star a shot at playing in the BIG3!!

The rap legend and three-on-three league co-founder got wind of what the Cleveland Browns defensive end said while watching his brother, Sean Williams, play for the Miami 305 in the BIG3 Championship last week … when Rachel Nichols asked the 6’4″, 272-pounder if he could see himself playing in the BIG3 too.

Garrett teased he’d love to test his talents … and Cube is on board — as long as he goes through the same process as everyone else.

FYI, Garret does have basketball experience. The Texas-native hooped in high school, along with being a football and track standout.

In fact — not too long ago, the former NFL Defensive Player of the Year slammed down a two-handed windmill in front of fans at Cleveland Cavaliers Summer League warm-ups.

The basketball career might have to hold off for just a little bit. Garrett, 29, signed a four-year contract extension worth $160 million in March.