A post-holiday storm will bring heavy rain, snow and hazardous winds across the Northern tier. Blizzard Warnings have been posted for Minnesota and Wisconsin, as 250,000 customers nation wide have already lost power.

DETROIT, MI – At least 20 cars and multiple semi-trucks have been involved in a massive pile-up on Interstate 75 in Detroit, Michigan amid a dangerous winter storm on Monday.

The Michigan Department of Transportation (DOT) said the crash happened around 11 a.m. and the road has been closed for about four hours.

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Tow trucks are still clearing all the vehicles and the DOT said they will salt and plow the route before opening to the public.

The area experienced a snow squall at the time of the crash, but the Michigan DOT said the cause is yet to be determined by Michigan State Police.

Think of a snow squall like a miniature blizzard with gusty winds that typically lasts less than an hour. Very high snowfall rates, on the order of 2 inches in 30 minutes, are not uncommon.

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Officials said only one minor injury was reported. The crash happened on the northbound side of the highway.

Stay with FOX Weather for the latest up-to-date information on this story.