Mississippi’s got one wild situation — a hostile STD-carrying monkey busted loose from a large trailer truck hauling primates after the semi flipped over on a highway, according to police.

The wreck went down Tuesday in Heidelberg, where the truck, containing several monkeys infected with hepatitis C, herpes, and COVID, crashed en route from Tulane University to a Florida testing lab.

Cops say six monkeys made a break for it — but five were destroyed, and one’s still on the loose. Witnesses shot camera footage that captured the surviving monkey climbing out of the trailer and wandering around in a rural area.

As for Tulane University, officials tell us — despite what the cops say — the primates in question belong to another entity and are “not infectious,” meaning they don’t have diseases. They add, “We are actively collaborating with local authorities and will send a team of animal care experts to assist as needed.”